The present study was carried out to investigate the antidiabetic properties of petroleum ether extract of beans of Cyamopsis tetragonoloba in alloxan (70 mg/kg intravenous) induced diabetic rats for two days. The induced diabetic rats exhibited high blood glucose level. In addition, the water intake was remarkably high while feed intake was decreased as compared with normal control group. The continuous oral administration of the extract at the dose of 250 and 500 mg/kg for 14 days was able to lower BGL The effect of extract was compared with standard drug i.e. glibenclamide. The extract yielded high tannin, gallic acids, coniferyl alcohol and epikatonic acid. These compounds have been reported to potentiate insulin secretion. The present study revealed that petroleum ether extract of Cyamopsis tetragonoloba possesses antihyperglycemic potential and thus could support ethnotherapeutic usage of this plant.
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